Sure, for each named site create a location block;
location /path1 {
root /etc/path1;
.......
}
location /path2 {
root /etc/path2;
.......
}
http://nginx.org/en/docs/http/ngx_http_core_module.html#location
location /path1 {
root /etc/path1;
.......
}
location /path2 {
root /etc/path2;
.......
}
http://nginx.org/en/docs/http/ngx_http_core_module.html#location